منابع مشابه
A model of sodium channels.
We have explored the permeation and blockage of ions in sodium channels, relating the channel structure to function using electrostatic profiles and Brownian dynamics simulations. The model used resembles the KcsA potassium channel with an added external vestibule and a shorter selectivity filter. The electrostatic energy landscape seen by permeating ions is determined by solving Poisson's equa...
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Decoding of 3D multi-view video coded bit-streams that are transmitted over noisy channels can suffer from error propagation in the space, time and view domains. To improve the quality of reconstructed 3D video, we propose adaptive Error Concealment (EC) algorithms to conceal the erroneous blocks of intra-coded and inter-coded frames. Our proposed algorithms adapt to the motion characteristics ...
متن کاملSubunits of Sodium Channels
The purified Na+ channel from rat brain consists of a (260 kDa), Bl (36 kDa), and ,192 (33 kDa) subunits. Pure ,t?l subunits were prepared from purified rat brain Na+ channels which had been adsorbed to hydroxylapatite resin and used to prepare specific anti-81 subunit antiserum. Antibodies purified from this antiserum by antigen affinity chromatography immunoprecipitate 12SI-labeled, purified ...
متن کاملArchitecture and pore block of eukaryotic voltage-gated sodium channels in view of NavAb bacterial sodium channel structure.
The X-ray structure of the bacterial sodium channel NavAb provides a new template for the study of sodium and calcium channels. Unlike potassium channels, NavAb contains P2 helices in the outer-pore region. Because the sequence similarity between eukaryotic and prokaryotic sodium channels in this region is poor, the structural similarity is unclear. We analyzed it by using experimental data on ...
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Buthotus schach is one of the dangers scorpion in Iran that belong to the Buthidae family. Toxins are existing in venom scorpion, modulate the ion channels by blocking or opening the pore of the channel or by altering the voltage gating and useful as pharmacological tools. In the present study, we investigated the effect of venom and its obtained fractions by gel filtrations on electrophysiolog...
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ژورنال
عنوان ژورنال: Nature
سال: 2001
ISSN: 0028-0836,1476-4687
DOI: 10.1038/35059188